Showing posts with label Medication Administration. Show all posts
Showing posts with label Medication Administration. Show all posts

Jul 23, 2015

Nursing Care for Hypertension......

Nursing can be a lot to take into sometimes. You have to study hundreds of diseases and pick out the most appropriate nursing actions to address them. But how do you do that when you have so much to learn? For cases such as hypertension, for example. Here’s a mnemonic trick that would help you remember the interventions needed and things to consider for hypertension.
When hypertensive, remember: DIURETIC
D -daily weight
If the patient is hypertensive or even suspected to be, then his/her weight must be monitored. He/she must be weighed daily. Indicators for risk of hypertension include obesity, abdominal obesity and weight gain.Weight gain was associated with increased risk of developing hypertension.On the other hand, weight-loss can lead to a significant drop in blood pressure.
I-Intake and Output

Intake and output of the patient must also be kept closely monitored. Sodium balance is precisely regulated by intake and output.High salt intake increases extracellular volume (ECV), blood volume, and cardiac output resulting in elevation of blood pressure. Normal blood pressure are attained by increased glomerular filtration and decreased sodium reabsorption. In some individuals, the kidneys have difficulty in excreting sodium, so the equilibrium is achieved at the expense of elevated blood pressure. At times, the sodium balance must be achieved via dialysis and ultrafiltration.
U-Urine Output
When BP is low, renal blood flow drops. This stimulates renin and angiotensin production by the kidney. Angiotensin is converted to angiotensin II in the lung. This is controlled by angiotensin-converting enzyme. Angiotensin II is a vasoconstrictor – which will increase SVR. Angiotensin II also stimulates the adrenal cortex to produce aldosterone. Aldosterone causes sodium and water to be retained by the kidney. This will increase the extra cellular fluid (ECF) volume and therefore the circulating blood volume. This is also supported by antidiuretic hormone (vasopressin) which is produced by the hypothalamus and released by the posterior pituitary in response to angiotensin II. Angiotensin II also stimulates thirst, leading to increased fluid intake.
R-Response of B/P
A person’s blood pressure is not fixed as it rises and falls throughout the day in response to what that person is doing and what is happening around him/her. It’s important that the BP be monitored so as to know whether it is responding appropriately to your interventions, or to modify the treatment regimen.
E-Electrolytes
Dietary choices, even the amount of electrolytes you consume, can influence the blood pressure. These electrolytes such as sodium and potassium play a major role in regulating a person’s blood pressure.One of the functions of electrolytes is the balance of fluid in and around your cells. Electrolytes partially break down in water to form an ion. When this occurs, they influence where the fluids inside your body go. Sodium boosts water retention, leading to excess fluid in blood vessels and higher blood pressure.
TI-Transient Ischemic Episodes (TIA)

A transient ischemic attack (TIA) occurs when blood flow to a part of the brain stops for a brief time.High blood pressure is the main risk for TIAs and stroke.
C-Complications: 4 Cs (CAD, CRF, CHF, CVA)
You also have to remember that if left untreated, hypertension can cause certain complications. Over time this extra pressure can increase your risk of a heart attack, stroke and kidney disease.High blood pressure can cause many different diseases of the heart and blood vessels (medically known as cardiovascular diseases) and can also damage the small blood vessels in your kidneys and stop them from working properly.

Sources:

Mar 23, 2015

pushing IV medication through the heparin lock device....

It’s your first day being on duty at the medical ward as a student nurse and you’re trying to learn everything that you could. Upon accompanying the staff nurse in her rounds, you note that she is carrying a syringe and is about to administer IV medication to a patient who has no IV. You look around the room for IV bottles, but still you can’t find any.
“Umm, excuse me ma’am. Is that for the patient?” you ask the staff nurse.

“Yes, it is,” she answers.
“But he has no IV line”
“Oh, Ms. X, this is to be given through the hep lock” she says as she motions to that tiny yellow thing sticking out from the patient’s hand.
Oh, that’s a heplock? You ask yourself since it’s your first time to see one and wonder how one gives medications through it
medication administration part 2 72 728 300x225 How to push IV medication through the heparin lock deviceSteps:
  1. Observe 10 Golden rules in the administration of the medication when introducing medication to the patient
  2. Verify doctor’s order sheet or prescription.
  3. Check medication card against the written doctor’s prescription
  4. Explain procedure to the patient (name of the medicine and action) before administration.
  5. Do hand hygiene before and after the procedure (use gloves especially for chemo drugs).
  6. Gather equipment to include/but not limit to IV tray, Normal Saline diluents or isotonic 2.5 cc syringes (2-3 pcs) as needed.
  7. Prepare medication to be administered, e.g, antibiotic, and draw it up into syringe.
  8. Fill a tuberculin syringe with Heparin solution. N.B. Heparin solution is usually prepared with 0.1 cc. Heparin plus 0.99 cc Normal Saline or isotonic solution as prescribed by theDoctor.
  9. Fill the 2.5cc syringe with isotonic solution or Normal Saline solution; 1cc each.
  10. If using Heparin Lock Device with 3-way stop cock with luer-lock, rotate the stop cock so that the line going to the patient is closed (this will prevent backflow of blood.)
  11. Remove the cover of the injection port aseptically and keep the sterility of the cover.
  12. Check the patency, open the IV line and inject NSS or isotonic solution to flush the heparin solution as prescribed by the Doctor.
  13. Close the IV line and remove saline syringe and insert medication syringe into the port. Give I.V. push 5-10 minutes for IV potent drug. For 2-3 I.V. Medications, give at least 30 minutes to 1 hour interval. After each drug administered via I.V. push, flush with 2-3 cc saline solution.
  14. Observe patient for any adverse reactions and do nursing intervention accordingly.
  15. Discard waste according to Health Care Waste Management (DOH/DENR).
  16. Document in the patient’s chart.



  •  Some Hospital Does Not Use Heparin Anymore
  • Normal Saline can take the place of Heparin. Studies have shown the efficacy of NSS. Heparin solution can be used if normal saline or isotonic is not available and as prescribed by the M.D.
  • Sources:
    Notes

    Mar 14, 2015

    Preoperative Medications.....

    Overview
    One of the important events during the preoperative phase of the surgical experience is the administration of preoperative medications. Not only are anesthetics administered during this time, but so as drugs that minimizes respiratory tract secretions. Medicating the client pre-procedure to reduce anxiety and promote relaxation may also be necessary.
    Medication History
    Before discussing about the preoperative medications that are used the nurse should obtain a medication history. This eliminates the possible life-threatening effects of drug interactions and allergic reactions to certain medications. During a medication history the following are done:
    • Document any medication the patient is using or has used in the past including over-the-counter (OTC) preparations and the frequency with which they are taken.
    • The anesthesiologist evaluates the potential effects of prior medication therapy and considers the length of time the patient has used the medications, the patient himself and the nature of the proposed surgery.
    Medications that cause particular concerns are the following:
    Adrenal corticosteroids

    1. DO NOT discontinue these drugs abruptly before the surgery.
    2. If discontinued abruptly, the patient may suffer from cardiovascular collapse is he or she has been taking steroids for some time.
    3. Before and after the surgery, a bolus of steroid may be administered intravenously immediately.
    Diuretics
    During anesthesia administration, thiazide diuretics may cause excessive respiratory depression from an associated electrolyte imbalance.
    Phenothiazines
    These medications may increase the hypotensive action of anesthetics
    Antidepressants
    Anesthetics have a hypotensive effect on the patient. Monoamine Oxidase inhibitors or MAOIs increase the hypotensive effects of anesthetics.
    Tranquilizers
    If medications such as diazepam, barbiturates and chlordiazapoxide are withdrawn suddenly anxiety, tension and even seizures may result.

    Insulin
    When a patient undergoing a surgery is diabetic, interaction between anesthetics and insulin must be considered.
    Antibiotics
    Neomycin, kanamycin and other “MYCIN” drugs may present problems when these medications are combined with a curariform muscle relaxation. Interruption of nerve transmission may occur and apnea due to respiratory paralysis may result when these drugs are combined.

    Additional Source: http://emedicine.medscape.com/article/284801-overview#aw2aab6b8

    Feb 18, 2015

    ACLS Drugs for you to Know.....

    ACLS protocol utilizes the highest quality pharmaceuticals in the field of emergency medicine. In order to prevent further injury, ACLS trained professionals initiate IV access or intubation in certain situations where immediate intervention is needed, such as serious cardiac events and stroke. In pre-hospital settings, these pharmaceuticals are vital to keep the person alive and stable during transport to a medical facility.
    The pharmacology used by ACLS providers is the same used in hospitals by physicians working with the same kind of medical emergencies. ACLS certification courses provide a vast amount of information about these drugs, and trainees learn to determine which drug to use in any given clinical situation through the different ACLS algorithms.
    Here are some of the most commonly used drugs for various cardiovascular events utilized in ACLS protocol:
    Ventricular Fibrillation/ Ventricular Tachycardia

    • Vasopressin: Used in the pulseless arrest algorithm to raise blood pressure and induce moderate vasoconstriction. Has been shown to be more effective than epinephrine during asystolic cardiac arrest.
    • Epinephrine: A drug with powerful vasoconstrictive effects, used to increase cardiac output. Can be given through IV/IO and endotracheal tube.
    • Amiodarone: Anti-arrhythmic agent used for various tachyarrythmias, administered through IV/IO.
    • Lidocaine: Used as an alternative in VT/VF cardiac arrest when amiodarone is ineffective.
    Bradycardia
    • Epinephrine: Increases heart rate, heart contractility, and conductivity through the AV node.
    • Atropine: Increases activity in the SA node by blocking the vagas nerve and increasing heart rate. Most commonly used drug for bradycardia.
    • Dopamine
    Tachycardia
    • Adenosine: The main drug used to treat supraventricular tachycardia (stable narrow-complex). It interrupts re-entry through the AV node and restores normal sinus rhythm. It is quickly absorbed by red blood cells before being metabolized by the body.
    • Beta-blockers: Neutralizes the effects of stress hormones and epinephrine (adrenaline), which can trigger or exacerbate tachyarrhythmias.
    • Dilitiazem
    • Digoxin
    • Amiodarone
    Asystole/PEA
    • Vasopressin
    • Epinephrine
    Acute Coronary Syndomes
    • Aspirin
    • Oxygen
    • Morphine
    • Nitroglycerin
    Acute Stroke
    • tPA-tissue: Breaks down blood clots in the treatment of embolic or thrombotic stroke.
    • Glucose (D50)
    • Plasminogen Activator
    All of these drugs have specific conditions and dosages for use. These drugs are very powerful, and also come with some serious side-effects, so ACLS providers must exercise caution and accurately determine the correct drug and dosages to use. ACLS training features comprehensive algorithms which professionals follow step-by-step to ensure that optimal pharmaceutical care is provided.
    Our ACLS Pharmaceuticals Review & Tips:
    As previously noted, ACLS is a series of medical procedures put in to action using step by step methods, in order to save a patient suffering from cardiac arrest or certain other similar medical emergencies. In addition to procedures and techniques, drugs and medications are also used to help manage a patient and bring him back to life.
    There are several sets of medications that are administered throughout the algorithms to keep the patient recovering, step by step. Furthermore, certain medications are to be administered immediately or in pre-hospital settings while other sets of medications are to be administered in the emergency room afterwards.
    For ACLS students, it is very important to thoroughly understand a few points regarding medication administration:
    • It is very important to know the nature of the drug/drugs
    • It is crucially important to understand the proper time for administering medications
    • It is also very important to understand the proper method of drug administration
    • The affect of medication is also to be understood, carefully.
    ACLS medications are administered for several purposes i.e. to keep a person alive and protecting and preparing the heart for later interventions.
    The American Heart Association has provided protocols for proper medication distribution and regularly updates these protocols from time to time. Hence, it is very important for all medical professionals to learn the ACLS protocols and keep updating themselves as needed. Here is a short outline of the medications administered throughout the Advanced Cardiac Life Support algorithm.

    Pre-Hospital Medications

    At the beginning of the Life Support procedure, there are several drugs that can be administered. These medications are aimed at instant relief and preparing a patient for further treatment. These medications may be administered:
    • Orally
    • Through Intravenous Injections also known as IV
    • Injected in Bones/IO
    • Through ET tube
    Only Paramedics are certified for drug administration and EMTs are not allowed to administer medications in an ambulance. However, under some conditions they are allowed to administer nitroglycerin for relieving chest pain and aspirin.
    The typical medications that are used during pre-hospital settings or in an ambulance are:
    • Atropine
    • Diltiazem
    • Adenosine
    • Epinephrine
    • Lidocaine
    • Magnesium
    • Verapamil
    • Vasopressin
    There are certain other drugs that are carried by ambulance personnel for relieving chest pain and other symptoms arising from cardiac arrest, aside from the aforementioned pharmaceuticals. A few of them are:
    • Aspirin
    • Dopamine
    • Sodium bicarbonate
    • Morphine
    • Calcium

    Emergency Room Medications

    After the patient reaches the emergency room, he is to be administered with several other medications for proper treatment. These drugs may belong to the primary or secondary groups of Advance Cardiac Life Support drugs. Primary ACLS medications are those which are to be administered to keep the patient alive and are generally administered in pre-hospital settings. However, due to storage or cost issues, there are certain drugs that cannot be carried in the ambulance and are given to the patient as soon as he arrives to the emergency room. On the other hand, secondary drugs are those which are to be administered to weed the root cause out.
    The medications that are normally administered in the emergency room settings are:
    • Digoxin or Amiodarone for normalizing abnormal heart rhythms
    • Drugs for flushing clots out of heart
    • Drugs for normalizing Blood pressure i.e. Beta blockers or ACE inhibitors
    • Drugs for thinning blood to prevent clot formation inside heart or arteries.
    In addition to these drugs, several other drugs are detailed in the ACLS protocols issued by the American Heart Association. The guidelines for Advanced Cardiac Life Support provide detailed algorithms for treating several cardiac conditions that may end up in arrest and procedures to fight these conditions in order to save lives. When proper clinical guidelines are coupled with proper or prescribed drugs, the recovery of patients is effective and fastidious.

    Ventricular Fibrillation

    Asystole/PEA

    Bradycardia

    Tachycardia

    Acute Coronary Syndrome

    • Oxygen
    • Aspirin
    • Nitroglycerine
    • Morphine
    • Fibrolynic Therapy
    • Heparin
    • Beta-blockers

    Acute Stroke Care

    • tPA (tissue plasminogen activator)
    • Glucose
    • Labetolo
    • Nitroprusside
    • Nicardipine
    • Aspirin

    Jan 11, 2012

    FDA Issues Public Health Advisory on Certain Pain Meds....

     


     
    January 9, 2012 — The US Food and Drug Administration (FDA) is advising patients and healthcare professionals of a potential problem with opiate products manufactured and packaged for Endo Pharmaceuticals by Novartis Consumer Health at its Lincoln, Nebraska, manufacturing site.

    In a telebriefing today, Edward Cox, MD, from the FDA's Center for Drug Evaluation of Research, said: "Due to problems incurred when these products were packaged and labeled at the site, it's possible that tablets from 1 product may have been retained in the packaging machinery, and then may have carried over into packaging of another product."

    "This could result in an incorrect pill of 1 medicine ending up in the bottle of another product," he said. "The likelihood of this occurring in medication dispensed to medication is low," he emphasized.
    According to the public health advisory the FDA posted today, the following products may be affected:

    • Opana ER (oxymorphone hydrochloride) extended-release tablets CII
    • Opana (oxymorphone hydrochloride) CII
    • oxymorphone hydrochloride tablets CII
    • Percocet (oxycodone hydrochloride and acetaminophen USP) tablets CII
    • Percodan (oxycodone hydrochloride and aspirin, USP) tablets CII
    • Endocet (oxycodone hydrochloride and acetaminophen USP) tablets CII
    • Endodan (oxycodone hydrochloride and aspirin, USP) tablets CII
    • morphine sulfate extended-release tablets CII
    • Zydone (hydrocodone bitartrate/acetaminophen tablets, USP) CIII
    •  
    "Endo Pharmaceuticals reports that they are aware of only 3 product mix-ups with respect to these products since 2009," Dr. Cox said. "Endo is not aware of any patient having experienced a confirmed product mix-up, nor any adverse events attributable to a product mix-up," he added.
    He also noted that an FDA review of the Adverse Event Reporting System database from January 1, 2009, through January 6, 2012, for the Endo Pharmaceutical opioid products manufactured at the Lincoln, Nebraska, facility failed to turn up any reports of adverse events directly related to manufacturing problems.
    The FDA advises patients and healthcare professionals to check any opiate medicines made by Endo in their possession and to ensure that all tablets are the same.

    "We are asking patients to check their medicines to look for any tablet of a different size, shape, or color from their regular medicine," Dr. Cox said. "We are asking pharmacists to perform a visual inspection when dispensing the potential affected Endo opioid medications, according to the instructions provided by FDA."
    For more information, patients and healthcare providers can also contact Endo Pharmaceuticals' call center at 1-800-462-3636.

    In the advisory, the FDA says they expect there will be "periods of shortages for these products" in the coming weeks, and they are actively working with Endo Pharmaceuticals and Novartis to "minimize the degree of impact."
    As a precautionary measure, Novartis Consumer Health has initiated a voluntary recall of the other nonopiate products made at their Lincoln, Nebraska, manufacturing facility.
    These products include all lots of Excedrin and NoDoz products with expiration dates of December 20, 2014, or earlier, as well as Bufferin and Gas-X Prevention products with expiration dates of December 20, 2013, or earlier, in the United States.

    Healthcare professionals and patients are encouraged to report adverse events related to the use of these products to MedWatch, the FDA's safety information and adverse event reporting program, by telephone at 1-800-FDA-1088, by fax at 1-800-FDA-0178, online at https://www.accessdata.fda.gov/scripts/medwatch/medwatch-online.htm, or by mail to MedWatch, FDA, 5600 Fishers Lane, Rockville, Maryland 20852-9787.

    Sep 19, 2011

    FDA approves Xarelto to reduce risk of blood clots after hip, knee replacements....


    FDA NEWS RELEASE

    Media Inquiries: Erica Jefferson, 301-796-4988, erica.jefferson@fda.hhs.gov
    Consumer Inquiries: 888-INFO-FDA
    FDA approves Xarelto to reduce risk of blood clots after hip, knee replacements
    On July 1, the U.S. Food and Drug Administration approved Xarelto (rivaroxaban) to reduce the risk of blood clots, deep vein thrombosis (DVT), and pulmonary embolism (PE) following knee or hip replacement surgery.

    Xarelto is a pill taken once daily. Those undergoing a knee replacement should take the medication for 12 days and patients undergoing a hip replacement procedure should take Xarelto for 35 days.
    The safety and effectiveness of Xarelto was evaluated in patients undergoing hip replacement surgery and patients undergoing knee replacement surgery. Clinical studies were designed to identify occurrence of venous thromboembolic events (VTE), DVT, PE or death in patients treated. Treatment with Xarelto was compared to treatment with enoxaparin, a drug that prevents DVTs or blood clotting.
    “Xarelto represents a new oral treatment option to help prevent blood clotting in patients receiving a hip or knee replacement,” said Richard Pazdur, M.D., director of the Office of Oncology Drug Products in the FDA’s Center for Drug Evaluation and Research. Xarelto was reviewed by the Division of Hematology Products within the Office of Oncology Drug Products.

    More than 6,000 patients undergoing hip or knee replacement surgery received Xarelto in clinical studies. Among patients undergoing knee replacement surgery, 9.7 percent of those treated with Xarelto had VTE compared with 18.8 percent of patients who received enoxaparin. In a study involving hip replacement surgery, 1.1 percent of patients who received Xarelto had VTE compared with 3.9 percent of those who received enoxaparin. In another study of hip replacement patients, 2.0 percent of those treated with Xarelto had VTE compared with 8.4 percent of those who received enoxaparin.
    The most common side effect observed in patients treated with Xarelto was bleeding.
    Other FDA approved drugs to prevent blood clotting include Lovenox (enoxaparin), generic versions of enoxaparin, Arixtra (fondaparinux), Fragmin (dalteparin) for hip replacement surgery only, Coumadin (warfarin) and heparin.

    Xarelto is marketed in the U.S. by Raritan, N.J.- based Janssen Pharmaceuticals, Inc., a member of the Janssen Pharmaceutical Companies of Johnson & Johnson.

    For more information:
    The FDA, an agency within the U.S. Department of Health and Human Services, protects the public health by assuring the safety, effectiveness, and security of human and veterinary drugs, vaccines and other biological products for human use, and medical devices. The agency also is responsible for the safety and security of our nation’s food supply, cosmetics, dietary supplements, products that give off electronic radiation, and for regulating tobacco products.


    Visit the FDA on Facebook

    Sep 11, 2011

    Diabetes, Heart Disease, and Stroke....

    Diabetes and heart health

    Diabetes raises the chances of developing heart problems... eating well and getting or staying active. Even if you have had a heart attack already, you can do a lot more than just take medicines your doctor prescribes.

    What causes heart disease?


    Atherosclerosis is when, over time, fat deposits from cholesterol build up on the walls of your arteries. As the fat builds up, less blood is flows through. If the blood to your heart is blocked enough, you have a heart attack. If these fat deposits break loose, the result is a stroke. This is why doctors focus on reducing cholesterol.
    Diabetes is also more likely to cause heart problems due to damage from high glucose levels and high blood pressure.

    Managing A1c levels

    A1c is a measure of your blood sugar control over a period of time....daily testing for glucose levels will help manage how well you feel. Regular A1c tests help you know what steps you have to take to keep your blood sugar under control to protect your heart.

    Managing blood pressure

     High blood pressure can cause heart and kidney disease. Some people can reduce it with changes in diet or physical activity. Others require medicines. Your doctor or doctors will help you make the best decision for your specific situation.

    Managing cholesterol

     This chart shows you what most doctors agree are good measures of the scores you get.
    Normal less than 150 mg/dL
    Borderline High 150-199 mg/dL
    High 200-499 mg/dL
    Very High 500 mg/dL


    What are the risk factors for heart disease and stroke in people with diabetes?

    Diabetes itself is a risk factor for heart disease and stroke. Also, many people with diabetes have other conditions that increase their chance of developing heart disease and stroke. These conditions are called risk factors. One risk factor for heart disease and stroke is having a family history of heart disease. If one or more members of your family had a heart attack at an early age (before age 55 for men or 65 for women), you may be at increased risk.
    You can't change whether heart disease runs in your family, but you can take steps to control the other risk factors for heart disease listed here:
    • Having central obesity. Central obesity means carrying extra weight around the waist, as opposed to the hips. A waist measurement of more than 40 inches for men and more than 35 inches for women means you have central obesity. Your risk of heart disease is higher because abdominal fat can increase the production of LDL (bad) cholesterol, the type of blood fat that can be deposited on the inside of blood vessel walls.


    • Having abnormal blood fat (cholesterol) levels.
      - LDL cholesterol can build up inside your blood vessels, leading to narrowing and hardening of your arteries-the blood vessels that carry blood from the heart to the rest of the body. Arteries can then become blocked. Therefore, high levels of LDL cholesterol raise your risk of getting heart disease.

      - Triglycerides are another type of blood fat that can raise your risk of heart disease when the levels are high.

      - HDL (good) cholesterol removes deposits from inside your blood vessels and takes them to the liver for removal. Low levels of HDL cholesterol increase your risk for heart disease.


    • Having high blood pressure. If you have high blood pressure, also called hypertension, your heart must work harder to pump blood. High blood pressure can strain the heart, damage blood vessels, and increase your risk of heart attack, stroke, eye problems, and kidney problems.


    • Smoking. Smoking doubles your risk of getting heart disease. Stopping smoking is especially important for people with diabetes because both smoking and diabetes narrow blood vessels. Smoking also increases the risk of other long-term complications, such as eye problems. In addition, smoking can damage the blood vessels in your legs and increase the risk of amputation.


    What is metabolic syndrome and how is it linked to heart disease?

    Metabolic syndrome is a grouping of traits and medical conditions that puts people at risk for both heart disease and type 2 diabetes. It is defined by the National Cholesterol Education Program as having any three of the following five traits and medical conditions:
    Traits and Medical Conditions Definition
    Elevated waist circumference Waist measurement of
    • 40 inches or more in men
    • 35 inches or more in women
    Elevated levels of triglycerides
    • 150 mg/dL or higher
      or
    • Taking medication for elevated triglyceride levels
    Low levels of HDL (good) cholesterol
    • Below 40 mg/dL in men
    • Below 50 mg/dL in women
      or
      Taking medication for low HDL cholesterol levels
    Elevated blood pressure levels
    • 130 mm Hg or higher for systolic blood pressure or
    • 85 mm Hg or higher for diastolic blood pressure
      or
      Taking medication for elevated blood pressure levels
    Elevated fasting blood glucose levels
    • 100 mg/dL or higher
      or
    • Taking medication for elevated blood glucose levels
    Source: Grundy SM, et al. Diagnosis and Management of the Metabolic Syndrome: An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation. 2005;112:2735-2752.
    Note: Other definitions of similar conditions have been developed by the American Association of Clinical Endocrinologists, the International Diabetes Federation, and the World Health Organization.
    [

    What can I do to prevent or delay heart disease and stroke?

    Even if you are at high risk for heart disease and stroke, you can help keep your heart and blood vessels healthy. You can do so by taking the following steps:

    • Make sure that your diet is "heart-healthy." Meet with a registered dietitian to plan a diet that meets these goals:
      • Include at least 14 grams of fiber daily for every 1,000 calories consumed. Foods high in fiber may help lower blood cholesterol. Oat bran, oatmeal, whole-grain breads and cereals, dried beans and peas (such as kidney beans, pinto beans, and black-eyed peas), fruits, and vegetables are all good sources of fiber. Increase the amount of fiber in your diet gradually to avoid digestive problems.
      • Cut down on saturated fat. It raises your blood cholesterol level. Saturated fat is found in meats, poultry skin, butter, dairy products with fat, shortening, lard, and tropical oils such as palm and coconut oil. Your dietitian can figure out how many grams of saturated fat should be your daily maximum amount.
      • Keep the cholesterol in your diet to less than 300 milligrams a day. Cholesterol is found in meat, dairy products, and eggs.
      • Keep the amount of trans fat in your diet to a minimum. It's a type of fat in foods that raises blood cholesterol. Limit your intake of crackers, cookies, snack foods, commercially prepared baked goods, cake mixes, microwave popcorn, fried foods, salad dressings, and other foods made with partially hydrogenated oil. In addition, some kinds of vegetable shortening and margarines have trans fat. Check for trans fat in the Nutrition Facts section on the food package.

    • Make physical activity part of your routine. Aim for at least 30 minutes of exercise most days of the week. Think of ways to increase physical activity, such as taking the stairs instead of the elevator. If you haven't been physically active recently, see your doctor for a checkup before you start an exercise program.
    • Reach and maintain a healthy body weight. If you are overweight, try to be physically active for at least 30 minutes a day, most days of the week. Consult a registered dietitian for help in planning meals and lowering the fat and calorie content of your diet to reach and maintain a healthy weight. Aim for a loss of no more than 1 to 2 pounds a week.
    • If you smoke, quit. Your doctor can help you find ways to quit smoking.

    •  
    • Ask your doctor whether you should take aspirin. Studies have shown that taking a low dose of aspirin every day can help reduce the risk of heart disease and stroke. However, aspirin is not safe for everyone. Your doctor can tell you whether taking aspirin is right for you and exactly how much to take.
    • Get prompt treatment for transient ischemic attacks (TIAs). Early treatment for TIAs, sometimes called mini-strokes, may help prevent or delay a future stroke. Signs of a TIA are sudden weakness, loss of balance, numbness, confusion, blindness in one or both eyes, double vision, difficulty speaking, or a severe headache.


    How will I know whether my diabetes treatment is working?

    You can keep track of the ABCs of diabetes to make sure your treatment is working. Talk with your health care provider about the best targets for you.
    A stands for A1C (a test that measures blood glucose control). Have an A1C test at least twice a year. It shows your average blood glucose level over the past 3 months. Talk with your doctor about whether you should check your blood glucose at home and how to do it.
    A1C target
    Below 7 percent


    Blood glucose targets
    Before meals 90 to 130 mg/dL
    1 to 2 hours after the start of a meal Less than 180 mg/dL
    B is for blood pressure. Have it checked at every office visit.
    Blood pressure target
    Below 130/80 mm Hg
    C is for cholesterol. Have it checked at least once a year.
    Blood fat (cholesterol) targets
    LDL (bad) cholesterol Under 100 mg/dL
    Triglycerides Under 150 mg/dL
    HDL (good) cholesterol For men: above 40 mg/dL
    For women: above 50 mg/dL
    Control of the ABCs of diabetes can reduce your risk for heart disease and stroke. changes in diet, activity, and medications can help reach  goals.


    What types of heart and blood vessel disease occur in people with diabetes?

    Two major types of heart and blood vessel disease, also called cardiovascular disease, are common in people with diabetes: coronary artery disease (CAD) and cerebral vascular disease. People with diabetes are also at risk for heart failure. Narrowing or blockage of the blood vessels in the legs, a condition called peripheral arterial disease, can also occur in people with diabetes.

    Coronary Artery Disease

    Coronary artery disease, also called ischemic heart disease, is caused by a hardening or thickening of the walls of the blood vessels that go to your heart. Your blood supplies oxygen and other materials your heart needs for normal functioning. If the blood vessels to your heart become narrowed or blocked by fatty deposits, the blood supply is reduced or cut off, resulting in a heart attack.

    Cerebral Vascular Disease

    Cerebral vascular disease affects blood flow to the brain, leading to strokes and TIAs. It is caused by narrowing, blocking, or hardening of the blood vessels that go to the brain or by high blood pressure.

    Stroke

    A stroke results when the blood supply to the brain is suddenly cut off, which can occur when a blood vessel in the brain or neck is blocked or bursts. Brain cells are then deprived of oxygen and die. A stroke can result in problems with speech or vision or can cause weakness or paralysis. Most strokes are caused by fatty deposits or blood clots-jelly-like clumps of blood cells-that narrow or block one of the blood vessels in the brain or neck. A blood clot may stay where it formed or can travel within the body. People with diabetes are at increased risk for strokes caused by blood clots.
    A stroke may also be caused by a bleeding blood vessel in the brain. Called an aneurysm, a break in a blood vessel can occur as a result of high blood pressure or a weak spot in a blood vessel wall.

    TIAs

    TIAs are caused by a temporary blockage of a blood vessel to the brain. This blockage leads to a brief, sudden change in brain function, such as temporary numbness or weakness on one side of the body. Sudden changes in brain function also can lead to loss of balance, confusion, blindness in one or both eyes, double vision, difficulty speaking, or a severe headache. However, most symptoms disappear quickly and permanent damage is unlikely. If symptoms do not resolve in a few minutes, rather than a TIA, the event could be a stroke. The occurrence of a TIA means that a person is at risk for a stroke sometime in the future.

    Heart Failure

    Heart failure is a chronic condition in which the heart cannot pump blood properly-it does not mean that the heart suddenly stops working. Heart failure develops over a period of years, and symptoms can get worse over time. People with diabetes have at least twice the risk of heart failure as other people. One type of heart failure is congestive heart failure, in which fluid builds up inside body tissues. If the buildup is in the lungs, breathing becomes difficult.

    Blockage of the blood vessels and high blood glucose levels also can damage heart muscle and cause irregular heart beats. People with damage to heart muscle, a condition called cardiomyopathy, may have no symptoms in the early stages, but later they may experience weakness, shortness of breath, a severe cough, fatigue, and swelling of the legs and feet. Diabetes can also interfere with pain signals normally carried by the nerves, explaining why a person with diabetes may not experience the typical warning signs of a heart attack.

    Peripheral Arterial Disease

    Another condition related to heart disease and common in people with diabetes is peripheral arterial disease (PAD). With this condition, the blood vessels in the legs are narrowed or blocked by fatty deposits, decreasing blood flow to the legs and feet. PAD increases the chances of a heart attack or stroke occurring. Poor circulation in the legs and feet also raises the risk of amputation. Sometimes people with PAD develop pain in the calf or other parts of the leg when walking, which is relieved by resting for a few minutes.
     

    How will I know whether I have heart disease?

    One sign of heart disease is angina, the pain that occurs when a blood vessel to the heart is narrowed and the blood supply is reduced. You may feel pain or discomfort in your chest, shoulders, arms, jaw, or back, especially when you exercise. The pain may go away when you rest or take angina medicine. Angina does not cause permanent damage to the heart muscle, but if you have angina, your chance of having a heart attack increases.
    A heart attack occurs when a blood vessel to the heart becomes blocked. With blockage, not enough blood can reach that part of the heart muscle and permanent damage results. During a heart attack, you may have
    • chest pain or discomfort
    • pain or discomfort in your arms, back, jaw, neck, or stomach
    • shortness of breath
    • sweating
    • nausea
    • light-headedness
    Symptoms may come and go. However, in some people, particularly those with diabetes, symptoms may be mild or absent due to a condition in which the heart rate stays at the same level during exercise, inactivity, stress, or sleep. Also, nerve damage caused by diabetes may result in lack of pain during a heart attack.
    Women may not have chest pain but may be more likely to have shortness of breath, nausea, or back and jaw pain. If you have symptoms of a heart attack, call 911 right away. Treatment is most effective if given within an hour of a heart attack. Early treatment can prevent permanent damage to the heart.
    Your doctor should check your risk for heart disease and stroke at least once a year by checking your cholesterol and blood pressure levels and asking whether you smoke or have a family history of premature heart disease. The doctor can also check your urine for protein, another risk factor for heart disease. If you are at high risk or have symptoms of heart disease, you may need to undergo further testing.


    What are the treatment options for heart disease?

    Treatment for heart disease includes meal planning to ensure a heart-healthy diet and physical activity. In addition, you may need medications to treat heart damage or to lower your blood glucose, blood pressure, and cholesterol. If you are not already taking a low dose of aspirin every day, your doctor may suggest it. You also may need surgery or some other medical procedure.
    For additional information about heart and blood vessel disease, high blood pressure, and high cholesterol, call the National Heart, Lung, and Blood Institute Health Information Center at 301-592-8573 or see www.nhlbi.nih.gov on the Internet.


    How will I know whether I have had a stroke?

    The following signs may mean that you have had a stroke:
    • sudden weakness or numbness of your face, arm, or leg on one side of your body
    • sudden confusion, trouble talking, or trouble understanding
    • sudden dizziness, loss of balance, or trouble walking
    • sudden trouble seeing out of one or both eyes or sudden double vision
    • sudden severe headache
    If you have any of these symptoms, call 911 right away. You can help prevent permanent damage by getting to a hospital within an hour of a stroke. If your doctor thinks you have had a stroke, you may have tests such as a neurological examination to check your nervous system, special scans, blood tests, ultrasound examinations, or x rays. You also may be given medication that dissolves blood clots.


    What are the treatment options for stroke?

    At the first sign of a stroke, you should get medical care right away. If blood vessels to your brain are blocked by blood clots, the doctor can give you a "clot-busting" drug. The drug must be given soon after a stroke to be effective. Subsequent treatment for stroke includes medications and physical therapy, as well as surgery to repair the damage. Meal planning and physical activity may be part of your ongoing care. In addition, you may need medications to lower your blood glucose, blood pressure, and cholesterol and to prevent blood clots.
    For additional information about strokes, call the National Institute of Neurological Disorders and Stroke at 1-800-352-9424 or see www.ninds.nih.gov on the Internet.

    • If you have diabetes, you are at least twice as likely as other people to have heart disease or a stroke.
    • Controlling the ABCs of diabetes-A1C (blood glucose), blood pressure, and cholesterol-can cut your risk of heart disease and stroke.
    • Choosing foods wisely, being physically active, losing weight, quitting smoking, and taking medications (if needed) can all help lower your risk of heart disease and stroke.
    • If you have any warning signs of a heart attack or a stroke, get medical care immediately-don't delay. Early treatment of heart attack and stroke in a hospital emergency room can reduce damage to the heart and the brain.



    Hope through Research

    The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is one of the National Institutes of Health (NIH) under the U.S. Department of Health and Human Services. The NIDDK conducts and supports research in diabetes, glucose metabolism, and related conditions. Several studies related to diabetes, heart disease, and stroke are under way.
    • The Look AHEAD (Action for Health in Diabetes) trial is studying whether strategies for weight loss in obese people with type 2 diabetes can improve health. This trial is also sponsored by other NIH Institutes and by the Centers for Disease Control and Prevention. For more information on the Look AHEAD trial, visit the website at www.niddk.nih.gov/patient/SHOW/lookahead.htm.
    • The EDIC (Epidemiology of Diabetes Interventions and Complications) study is examining the long-term effects of prior intensive versus conventional blood glucose control. It is a follow-up study of patients who took part more than a decade ago in the Diabetes Control and Complications Trial (DCCT), a major clinical study funded by the National Institutes of Health.
    • The BARI 2D (Bypass Angioplasty Revascularization Investigation 2 Diabetes) trial, sponsored by the National Heart, Lung, and Blood Institute, in partnership with NIDDK, is studying approaches to the medical care of people with type 2 diabetes who also have coronary artery disease. For more information on the BARI 2D trial, visit the website at www.bari2d.org Exit Disclaimer image or call the nearest research center (listed on the website).
    • The ACCORD (Action to Control Cardiovascular Risk in Diabetes) trial is studying three approaches to preventing major cardiovascular events in individuals with type 2 diabetes. For more information on the ACCORD trial, visit the website at www.accordtrial.org Exit Disclaimer image or call 1-888-342-2380.
    • The NIDDK and other components of the NIH will continue to fund research on the best ways to enhance health promotion, self-management, and risk reduction in people with diabetes.